Contraindications. Tabletki należy połykać, popijając niewielką ilością wody. <insert manic paragraph describing our speedy community in vivid detail, describing at great length the community, the rules, the daily goings-on etc., hopefully with many run-on sentences and a general lack of focus or point> Also consider supporting Psychonaut Wiki & Erowid as they provide invaluable information for free to anyone who needs it. Does Memantine HCL Interact with other Medications? Dawkę, okres oraz częstotliwość stosowania ustala lekarz. I have one question for you:If you've taken 300mg in about a 4 hour period, how much would you think you would need to reach the "Mem-Hole"? Its name is derived from its structure; 3,5-dimethyladamantan-1-amine. There's a reasonable amount of people (myself included) who thoroughly enjoy memantine's recreational effects. For more information on Memantine read: Memantine Wikipedia Hey I can contribute! So I'm seeing a psychiatrist to see about getting back on my vyvanse in order to help with going back to school(I would just use RC stims as they work better, really, but I'm getting put on probation in two weeks and have to take hair follicle tests). I have a lot of experience. You may need to read it again. Keiski, in New Therapeutics for Traumatic Brain Injury, 2017. Welcome to r/DXM - the official subreddit for discussion of the powerful dissociative cough suppressant - Dextromethorphan! I imagine that's because I don't eat enough/keep myself hydrated enough during the previous day. Cough 4. I will personally be compiling user reports from erowid and any pre-existing reports on reddit, but there is limited information available. (note: I'm a ~70kg male). That's how it is for me at least. At the peak of the dissociation, I find it difficult to communicate with people (mainly via text). A subreddit dedicated to people who have there own drug gardens. Serious Interactions. In conjunction with the psychonaut wiki, we are seeking to create a more reliable and standardized recommended dosing range for recreational use of Memantine. Once you finally feel the urge to go curl up in your bed under your blankets, don't be surprised if you sleep for 16 hours straight. I wasn't noticing much effects(I bought it basically for recreational use but read that even taking this much could be intoxicating after a couple of days). Press question mark to learn the rest of the keyboard shortcuts. Press J to jump to the feed. Memantine hydrochloride extended-release capsules were evaluated in a double-blind placebo-controlled trial in which a total of 676 patients with moderate to severe dementia of the Alzheimer’s type (341 patients on memantine hydrochloride extended-release capsules 28 mg/day and 335 patients on placebo) for a treatment period up to 24 weeks. Store memantine at room temperature away from moisture and heat. It's mainly about the recreational use of DPH, but posts about using DPH as it was intended are welcome, too. For me, nothing works. The self awareness memantine provides is one of the key factors why I enjoy it over other dissos, you can very easily gauge how much it is effecting you and take precautions so your situation is rarely ever precarious. I've taken as high as 200mg (with tolerance). Confused 2. Both the research  and anecdotal reports  recount as much. Definitely has similar numbing qualities as other dissociatives. One interesting memantine side effect includes higher libido. It is taken by mouth. Thanks for the insight, I know you're one of the first other recreational users I came across on reddit. Multiple trials have found that memantine can attenuate some of the side-effects of cocaine abuse. For people who enjoy both gardening and drugs. It's a lot of the not so great effects ketamine has with none of the good effects. I weigh 120lbs-125lbs. r/depressionregimens is a sub for redditors with depression and anxiety who are looking to be part of a constructive community dedicated towards improvement, with a focus on safe and researched substances. The only positive is it's pretty good at getting rid of anxiety, your brain isn't working enough to be anxious. Memantine is a prescription drug. NAMENDA oral solution contains memantine hydrochloride in a strength equivalent to 2 mg of memantine hydrochloride in each mL. The supplements subreddit aims to discuss and share topics related to nutritional supplementation. For the discussion of recreational pharmacology. It's difficult to tell if you've reached the Mem-Hole or not, because in my experience, to really achieve it you have to find a very calm place, allow your mind to drift and more or less meditate for a lack of a better term, until you've disconnected from reality. memantine Hydrochloride 10 mg tablet: round, film-coated tablets are gray, with the strength (M10) debossed on one side and X on the other. Memantine is great. Well it got to be pretty late in the evening to I attempted to get to bed, but at 300mg there was no way I slept very much. Pictures and discussions. Feel free to ask me any questions. on the real, a place for humans who prefer to go fast (in whatever way they like) to come together, commune, communicate, share stories of our lives, ask questions, share knowledge (always in the interest of harm reduction), make friends, and revel in the wonders of life. If you don't see your submission or have a problem feel free to message the moderators. There is some clinical evidence that it can help people recover from stimulant and opioid addictions. These medications may interact and cause very harmful effects. Results: Pretreatment with memantine attenuated the craving for alcohol before alcohol administration, but not after alcohol was given. Trying 50mg Memantine tonight. Confidence issues are because I feel that I haven't accomplished anything in my life besides a highschool diploma. Memantine hydrochloride was evaluated in eight double-blind placebo-controlled trials involving a total of 1862 dementia (Alzheimer's disease, vascular dementia) patients (940 patients treated with memantine hydrochloride and 922 patients treated with placebo) for a treatment period up to 28 weeks. I find myself over-analyzing everything. But it is very pleasant sleep. This is yet another reason why I love this substance, I don't think I've had such a clean and clear headed disconnection from reality without feeling heavily impaired at the same time. Also known as: Namenda, Namenda XR. MDL number MFCD00214336. Molecular Weight 215.76 . When you first start taking this medication, you will usually take it once daily. Treatment should only be continued if beneficial effects are seen. I got a little bit of double vision as this dose, with a slight amount of other dissociatives visuals, mainly scenery slicing. Discussion of nootropics and cognitive enhancers. Hi, it seems like this is a subreddit for the recreational use of Memantine (sorry if I'm mistaken), which makes me a bit worried that it was prescribed for my father (Ebixa 10 mg, pill a day for 1 month) as a treatment for his sudden memory/cognitive issues due to Small Vessel Disease. Memantine Vipharm należy przyjmować doustnie, raz na dobę. Memantine is a useful nootropic in the 10mg-60mg range daily, ONCE YOU GET USED TO IT, which can take a couple months, and slows opiate and stimulant tolerance buildup a bit. Welcome to the place for discussion of kratom. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Keep the liquid medicine bottle tightly closed with the cap provided. Find more subreddits like r/MemantineHCl -- A sub for discussing all uses of Memantine, from therapeutic to recreational. Make sure you follow the RULES. This includes new research, potential supplement choices (ie. I was able to mix 50 mg of memantine hydrochloride into 1 ml of distilled water only after applying light heat to increase solubility. Memantine HCl occurs as a fine white to off-white powder and is soluble in water. Haven't felt any Euphoria yet within 2hrs of taking it initially at 10.00pm. It just takes time. It's a looooong trip. YOU WILL BE BANNED FOR ASKING OR PROVIDING DRUG OR PARAPHERNALIA SOURCES, whether illegal or legal. Strictly no sourcing. It was when I found a source or Memantine powder that I started experimenting with more recreational doses. Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. Get your prescription refilled before you run out of medicine completely. I was pretty dissociated but it lacked the euphoria and pretty much any 'fun' aspect of a recreational dissociative. A dedicated subreddit for the discussion of synthetic psychoactive research chemicals. The tablet can be divided into equal doses. (Examples: Dexamyl, Placidyl, Diconal, Miltown). For full subreddit functionality, we recommend OPTING OUT of the redesign in your settings! Cholinesterase inhibitors may be added to memantine for further beneficial effects on behavioral symptoms and other … The FDA has officially approved memantine for the treatment of certain cases of Alzheimer’s disease, and this is the most typical medical use of memantine. I personally have replaced all other dissociative use (including a previous Ketamine addiction, and regular DXM use) with Memantine. Memantine hydrochloride 10 mg film-coated tablets are pale yellow to yellow, oval shaped film-coated tablets with breaking line and engravings 1 0 on one side and R R on the other side. Memantine may be useful for treating substance abuse and dependence. 1st time, 100mg : This drug takes a while to come up on that's for sure. I am interested in getting it again though and using it for tolerance to stimulants because long story short, I have crippling anxiety, have used benzos for it, they make it way worse and have caused a lot of problems for me, I've basically came to the conclusion that I'm anxious because of confidence issues. memantine Hydrochloride Tablet is contraindicated in patients with known hypersensitivity to memantine hydrochloride or to any excipients used in the formulation. It has a role as a dopaminergic agent, an antiparkinson drug, a NMDA receptor antagonist, a neuroprotective agent and an antidepressant. I had pretty intense close eyed visuals for most of the night, not really knowing if I slept at all when I got of bed the next day. Then memantine is pulled into the channel to its binding site. This drug will pretty much wreck your dissociative tolerance, so don't plan on getting much fun out of any other dissos for weeks or maybe months after a recreational dose of memantine. We are a migrant community mostly from the previous sub NovelDissos. Do some dreaming, ask a question, get a ban. * Combinations you tried or want to try EC Number 255-219-6. This subreddit is mostly powered by research from [Examine.com](http://examine.com/), and some reading of the supplement on hand (either at this site or other sources) before posting is encouraged to facilitate discussion. As for your comment about car accidents, any reasonable user should be smart enough and aware of the dangers of driving on any substance, this sub and the other resources available are meant to reduce harm and educate users about the risks involved with Memantine use. Memantine is substituted with a methyl carbon at both R3 and R5; it contains an amine substitution at R1. Take this medication by mouth with or without food as directed by your doctor. The things that do work/produce an effect will eventually have a deleterious effect on the mind. Memantine (0, 15, and 30 mg) was administered 4 h before alcohol (1.5 g/l body water), which was given in four divided doses every 20 min. Theres also a memantine powder vendor on reddit, with great prices. There's no element of confusion at all. Examples: morning glory, peyote, San Pedro, datura, Hawaiian baby woodrose, mimosa hostilis, etc. Memantine, or 3,5-dimethyladamantan-1-amine, is a man-made molecule classified as a substituted adamantane derivative. Overall, this is a very long lasting drug, but even at high doses I felt l still felt pretty in control. The next day, I often feel achey and sore all over. Constipation 3. I'll continue to update this as I find more reports, and for the reports that do not explicitly state the strength of the effects, I've gauged the strength of effects based on the description of their experience. What can replace xxx? Memantine is a prescription drug used to treat moderate to severe confusion related to Alzheimer's disease.It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to perform daily functions.This medication works by blocking the action of a certain natural substance in the brain that is believed to be linked to symptoms of Alzheimer's disease. 20mg per mL in a 30mL bottle. ), and general discussions on different categories of supplementation. A sub dedicated to PCP, Ketamine, MXE, Diphenidine, DXM, MK-801 and more! Memantine, 3-MEO-PCE, LSD, 4-AcO-MiPT, 4-HO-MET, 2C-C, Clonazepam & Aripiprazole: Adventures in NMDA Receptor Antagonism: viscosity: Memantine & DXM: Just the Kick in the Teeth I Was Looking For: 180OnTheDVP: Memantine & Nitrous Oxide: Beyond Tollerance Reduction: Clyde T. It is a long acting NMDA receptor antagonist that binds to an open channel binding site. All I can say is its a very clean dissociative. Keep this leaflet. But it wasn't very fun. A subreddit for the sharing and discussion of research chemical vendors. A psychonaut is a person who experiences intentionally induced altered states of consciousness and claims to use the experience to investigate his or her mind, and possibly address spiritual questions, through direct experience. But at the same time, I"m 100% consciously aware of the fact that my cognitive abilities are impaired. Discussion of all things related to the narcotics known as opiates, from harm-reduction to pharmacology. Dissociative Chemical Diffefence Image Chart: This has taken me several hours before and by the time I've reached the depths of the memanverse I've forgotten I was even in my bed before (or wherever), leaving me in great voids and dark, space-filled structures, with no thoughts about the outside world. And it lasts fucking forever, so you take 100mg and you don't like it, prepare to feel that way for three days and likely have a car accident and some serious amnesia. Excipient information presented when available (limited, particularly for generics); consult specific product labeling. Consequently, there is a large pool of high-quality evidence that supports memantine’s use in moderate-to-severe cases of Alzheimer’s disease (AD). I'm also a woman of normal height and weight (5'6"; 125 lbs). Memantine: Formulations, Dosages, Contraindications, and Side Effects. (r/drugs with longer words). Do some research, ask a question, get an answer. I didn't feel much with the first dose, possibly due to an increased tolerance since it wasn't super long since the last time I took it, (which I do not recommend... apparently taking it to often can fux with neuroplasticity levels), but a few hours after the second dose things got pretty warbly. HCl . Don't take phenibut before you understand the risks and side effects. Memantine hydrochloride oral solution is a prescription medicine used for the treatment of moderate to severe dementia in people with Alzheimer's disease. Memantine oral tablet is … This is a subreddit about DPH. I can already say this is my alternative to DXM. This includes: URLs, markets, PMs, etc. If one does not mind waiting a few hours for the effects to be felt, and due to the pain involved with intramuscular injection, I believe … http://scs-assets-cdn.vice.com/int/v18n2/htdocs/interview-with-ketamine-chemist-704/drug-structures.gif. Memantine HCl is an antagonist of NMDAR.It is also a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with IC50 of 1.12 μM and 242.4 μM, … Feel free to share helpful hints, tips, and news about kratom. I've also tabulated this data for easier reading: I was gonna post my report haha thank you for beating me to it. Vision is clearly distorted and physical balance is off. I'm pretty experienced with dissociatives, so it had been a while since I've felt something I could compare to a true-robo walk, but this seemed to fit the bill. When in doubt, DONT. Memantine is used to manage moderate to severe Alzheimer's dementia Label.. A more recent systemic review and meta-analysis 6 indicates that memantine is beneficial as a first line drug for the treatment of Alzheimer's dementia. I took 150mg the next day and had a Bon fire. Memantine hydrochloride 10 mg Film-Coated Tablets Memantine hydrochloride 20 mg Film-Coated Tablets Memantine hydrochloride Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. View Entire Discussion (30 Comments) More posts from the Nootropics community. * DPH as a lifestyle A sub for discussing all uses of Memantine, from therapeutic to recreational. Also you mentioned this 'doll-house' type effect, I've been coining the term 'Memanverse' to describe what I think you are saying. These are currently the few reliable reports of recreational Memantine use: Reported Dose: 150mgDescribed Experience: Heavy (Hole-like experience)Reported Tolerance: unknown, some dissociative experienceSource: https://erowid.org/experiences/exp.php?ID=109838, Reported Dose: 150mgDescribed Experience: Heavy (Hole-like experience)Reported Tolerance: Experienced userSource: https://erowid.org/experiences/exp.php?ID=109789, Reported Dose: 20mg (In conjunction with 600mg of Gabapentin)Described Experience: Threshold-LightReported Tolerance: Zero experience with Memantine, some experience with other dissociativesSource: https://erowid.org/experiences/exp.php?ID=105696, Reported Dose: 100mgDescribed Experience: Common-StrongReported Tolerance: some dissociative experienceSource: https://erowid.org/experiences/exp.php?ID=100894, Reported Dose: 100mgDescribed Experience: CommonReported Tolerance: unknown, user reports previous use of DXMSource: https://drugs-forum.com/threads/100mg-memantine.248883/, Reported Dose: 4x doses ranging between 50-100mg (200-400mg total)Described Experience: HeavyReported Tolerance: unknownNote: recommends 50-100mg for common useSource: https://erowid.org/experiences/exp.php?ID=32398, Reported Dose: 80-100mgDescribed Experience: Light-CommonReported Tolerance: unknownSource: https://drugs-forum.com/threads/memantine-experience.286366/, (From the same thread as above)Reported Dose:50mg (1st Day), 90mg (2nd Day), 160mg (3rd Day)Described Experience:Day 1: (Light), Day 2: (Light-Common), Day 3: (Strong)Reported Tolerance: UnknownSource: https://drugs-forum.com/threads/memantine-experience.286366/, Reported Dose: 280mgDescribed Experience: Strong-HeavyReported Tolerance: unknownSource:https://drugs-forum.com/threads/memantine-experience-high-dose.296411/. That's basically all I have. I've taken memantine at 20mg/day for ~3 months, effectively, and recreationally/experimentally, once at 50 mg-common dose (effects: gnawing hunger/empty feeling in stomach, dizziness/"whoosh" feeling when moving my head, increased interest in everything, less/no fidgeting/increased concentration). A friend of mine liked it so I just gave it to him. I ended up getting too confident and falling down this hill and hitting my leg on a piece of concrete. I then took 50mg in the morning followed by 50mg more in the afternoon. I don't remember the exact dosage, but it didn't exceed 150mg. For those who want to use memantine for … Sourcing drugs is NOT allowed here! A subreddit for all benzodiazepine users to gather to discuss all things benzo related. Common side effects … Memantine has an average rating of 4.6 out of 10 from a total of 35 ratings for the treatment of Alzheimer's Disease. Memantine hydrochloride, USP occurs as a fine white to off-white powder and is soluble in water. Share the love! * Experiences you had with DPH I am done with my experimentation. Whether its a question, picture, or information. 348. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Pictures of drug and paraphernalia collections, and large amounts of drugs. Diarrhea 5. We are here to discuss all dissociative chemicals, reports, trips, possible chemical synthesis, and any sources you may come across. Ill continue later.... New comments cannot be posted and votes cannot be cast, More posts from the MemantineHCl community. Colors were much more defined, and everything became surreal almost as if it were placed there with some higher meaning, like the "doll-house" effect, maybe I should call it the "M-house" effect, lol. And personally, I've never had a bad time while under the influence. The 3rd time I took 150mg, followed by another 150mg about 4 hours later. If experienced, these tend to have a Less Severe expression 1. Memantine, or known as Memantine HcL, is an uncompetitive NMDA receptor antagonist, and thus relies on glutamate’s activation of the NMDA receptor to take effect. This includes prescription medications, street drugs and anything else with recreational potential that is uncommon or hard to find.